Outcomes Following Surgical Revascularization With Single Versus Bilateral Internal Thoracic Arterial Grafts in Patients With Left Main Coronary Artery Disease Undergoing Coronary Artery Bypass Grafting: Insights From the EXCEL Trial

Outcomes Following Surgical Revascularization With Single Versus Bilateral Internal Thoracic Arterial Grafts in Patients With Left Main Coronary Artery Disease Undergoing Coronary Artery Bypass Grafting: Insights From the EXCEL Trial

Eur J Cardiothorac Surg. 2018 Aug 27. doi: 10.1093/ejcts/ezy291.

https://www.ctsnet.org/jans/outcomes-following-surgical-revascularization-single-versus-bilateral-internal-thoracic?utm_source=iContact&utm_medium=email&utm_campaign=ctsnet&utm_content=JANS+12%2F7%2F2018


The EXCEL trial randomized 1905 patients with left main coronary artery disease to percutaneous coronary intervention with everolimus-eluting stents versus CABG.
Among the 905 patients undergoing CABG, 688 (76.0%) received SITA and 217 (24.0%) received BITA.

The unadjusted 3-year composite primary endpoint of
death, stroke or myocardial infarction (MI)  15.6% of SITA = 11.6% of BITA
all-cause death 6.7% = 3.3%
Sternal wound dehiscence within 30 days 1.8% = 2.2%  !!!

CONCLUSIONS:
In the EXCEL trial, there were no clinical differences at 3 years between SITA or BITA revascularization in patients with left main coronary artery disease.